A third person may have been ‘cured’ of HIV

A Man Has Reportedly Been Cured of HIV  AIDS- What Does This Mean For Africa

A bone marrow transplant is never done on patients who only have HIV alone.

But just like the protease inhibitors and triple therapy were not a cure in 1996, the eradication of HIV from the bodies of two men across more than a dozen years undergoing stem cell or bone marrow transplants with cells that have the CCR5 genetic mutation is simply not the promise of an impending cure for HIV for at least four important reasons: it is highly risky; it is extremely expensive; it is not scalable; and it is not sustainable.

Publishing in the science journal "Nature", researchers from University College London detail how they have achieved HIV remission in a man known publicly as the London Patient, making this the second of only two documented prolonged cases of remission of this kind in the world.

Both the London patient and the Düsseldorf patients' cases were announced publicly at this week's Conference on Retroviruses and Opportunistic Infections in Seattle, hence the quick succession.

It has been 12 years since the first HIV-cured patient was reported. Neither of these patients have stopped their antiviral drug regimens yet.

The Düsseldorf patient had a bone marrow transplant to treat cancer, the same as the other two patients said now to be HIV-free.

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In the United States, however, the Trump administration continues to chip away at federal funding for potentially life-saving HIV/AIDS research. It is typically reserved only for patients who have late-stage cancer and for whom standard cancer treatments have otherwise failed. As a result of this procedure, consistent with the famous "Berlin patient" Timothy Ray Brown, the "London patient" appears to be rid of measurable HIV virus. After receiving treatment, both patients were eventually taken off their anti-retroviral medications and subsequent examination showed that that even with very sensitive blood tests, the team could not detect HIV in their blood.

Around 22,000 people are known have the CCR5 mutation, and they are mostly northern European. The patient must then be monitored to insure that his or her HIV does not come roaring back.

Top panel illustrates the treatment course for the London patient.

HIV patients need lifelong treatment that can be costly and early and continuous treatment enables them to lead healthy lives and effectively eliminates the risk of sexual transmission to their partners, says a press release issued by the U.S. embassy on Friday.

Co-organised by Vietnam Authority for HIV/AIDS Control (VAAC), Ministry of Health and the US President's Emergency Plan for AIDS Relief (PEPFAR), the events mark an important milestone in securing domestic sustainable financing for the HIV response in Việt Nam and ensuring that people living with HIV access treatment services. "At the moment HIV isn't cured". HIV uses the protein to enter the cell, but it can not attach to the mutated version. This renders them resistant to most HIV infection.

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