Aspirin dose every day unnecessary for healthy older people

Many healthy older people self-medicate with a daily dose of aspirin

Around half of the participants took a 100mg low dose of aspirin daily, while the others were given a placebo.

The report informs consuming Aspirin might also increase the risk of a potential internal bleeding.

The results from the trial, published Sunday in three studies in the New England Journal of Medicine, show that the rate of cardiovascular disease was 10.7 events per 1,000 person-years in the aspirin group and 11.3 events per 1,000 person-years in the placebo group.

Research into almost 20,000 older people found those who were generally healthy derived no protective benefit from the blood-thinning pill - but it increased their risk of risky bleeds. He cautioned that the results do not apply to those with existing conditions such as a previous heart attack, angina or stroke, where aspirin is recommended as a valuable preventive drug. But the new study, known as ASPREE, looked at the long-standing question of whether a first heart attack, stroke, or case of heart failure could be prevented with small amounts of the blood thinner in aspirin.

Millions of healthy people who take aspirin to ward off illness in old age are unlikely to benefit from the drug, a trial has found.

But a study involving more than 19,000 participants has found that there is no significant advantage and that taking aspirin regularly can instead lead to a slightly increased risk of serious bleeding.

The randomised double-blind trial, called ASPREE, was conducted by Monash University in Australia and the Berman Centre for Outcomes and Clinical Research in the United States.

The trial has "provided convincing evidence that aspirin is ineffective in preserving good health in elderly people without a medical (reason) to be using it", chief author Dr John J. McNeil of Monash University in Melbourne told Reuters Health in an email.

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"These findings will help inform prescribing doctors, who have always been uncertain about whether to recommend aspirin to healthy patients who do not have a clear medical reason for doing so".

Among the people randomly assigned to take aspirin, 90.3 per cent remained alive at the end of the treatment without persistent physical disability or dementia, compared with 90.5 per cent of those taking a placebo. Bleeding is a well-known side effect of aspirin, and is more common in older people.

Although aspirin has proven to be effective after a heart stroke, it has no health benefit for those who are above 70, according to a study.

When the researchers looked at death, disability and dementia, they found virtually no difference between the aspirin-taking group and the group given a placebo: 21.5 events per 1000 person-years in the former and 21.2 per 1000 person-years in the latter.

Using the help of Global Positioning System, researchers recruited 16,703 older people in Australian and 2411 in the United States, with approximately 9500 people in both the aspirin and the placebo group.

Popping an aspirin pill everyday doesn't help older people to live longer and it may even have the opposite effect, a new study reveals.

The "tentative finding" required further investigation as researchers in other studies suggest aspirin may prevent cancer, he said.

"These findings will help inform prescribing doctors who have always been uncertain about whether to recommend aspirin to healthy patients who do not have a clear medical reason for doing so".

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